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On a mission to making Glut1 Deficiency a disease of the past.

WHAT IS GLUT1 DEFICIENCY

GLUT1 Deficiency Syndrome (GLUT1 DS) is a rare genetic disorder that affects the transportation of glucose (sugar) into the brain. Glucose is the brain’s primary source of energy, and when there’s a deficiency, it can lead to a variety of neurological problems. The condition results from mutations in the SLC2A1 gene, which codes for the GLUT1 protein, responsible for transporting glucose across the blood-brain barrier.

Types:

  1. Classic GLUT1 Deficiency Syndrome: Characterized by early-onset seizures, developmental delays, and movement disorders.

  2. Non-classic forms: These might include movement disorders or learning difficulties without seizures.

ABOUT US

Founded in 2024 as a 501(c)(3), The Isaacson Family Foundation raises awareness and makes strategic charitable investments in support of medical institutions whom are working tirelessly towards treating and curing Glut1 Deficiency Syndrome. Their youngest of four children, Hannah, suffers from this genetic disorder. Glut1 DS is a brain energy failure syndrome caused by impaired glucose transport across brain tissue barriers, causing symptoms such as eye‐head movement abnormalities, seizures, neurodevelopmental impairment, deceleration of head growth, and movement disorders. Currently, there is no cure. Raising awareness and raising funds go hand in hand when it comes to providing a better quality of life for those patients and families who are suffering. Together, we will aim to make Glut1 DS a disease of the past.

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Facts About
Glut1
Deficiency
Syndrome

Currently, there is no cure for patients who suffer with Glut1 Deficiency Syndrome. This condition is fairly newly recognized as it was discovered by Dr. Darryl DeVivo in 1991. It is estimated that 1 out of 24,000 people have Glut1 DS, yet there are only about 500 diagnosed in the United States. The research has been fast tracked, but there is still so much unknown on how the disorder affects a patient. 

HOW YOU
CAN HELP

Patient advocacy and disease awareness is the glue to raising funds to support the doctors and research projects. Please consider making a contribution.

Latest Research

Stay informed with our 'Latest Research' section, featuring a sliding box that showcases our most recent articles. Additionally, learn more about our cause with the 'What is Glut1 Deficiency' box, which will include a brief overview to educate and engage our visitors. Together, we can spread awareness and support those affected.

Events
  • The Isaacson Family Foundation x Manolo Blahnik
    The Isaacson Family Foundation x Manolo Blahnik
    The Isaacson Family Foundation x Manolo Blahnik
    December 10th, 2024
  • Isaacson Family Foundation fundraiser 2024
    Isaacson Family Foundation fundraiser 2024
    Isaacson Family Foundation fundraiser 2024
    August 6th, 2024
  • Inaugural Isaacson Family Foundation event
    Inaugural Isaacson Family Foundation event
    Inaugural Isaacson Family Foundation event
    July 2023
All the Latest Updates on Hannah

Stay updated on Hannah's progress and catch a glimpse of living with Glut1 Deficiency on our Instagram and Facebook pages! 

  • Instagram
Contact Us

For any inquiries or assistance, please feel free to reach out to us via email.We are here to help and will respond as soon as possible. Your questions and feedback are important to us!

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